Pinealon is the synthetic tripeptide L-glutamyl-L-aspartyl-L-arginine, written Glu-Asp-Arg or EDR in the literature. Its chemical identity record is PubChem CID 10273502: molecular formula C₁₅H₂₆N₆O₈, 418.40 g/mol, monoisotopic mass 418.1812 Da, CAS 175175-23-2. Check the salt state before you calculate a molarity. PubChem catalogues the acetate separately as CID 155977549, C₁₇H₃₀N₆O₁₀ at 478.5 g/mol — about 60 g/mol heavier than the free peptide above.
"Pinealon" is a trade-style name from the Russian peptide-bioregulator literature, not an international nonproprietary name. That matters for literature searches: the sequence forms (Glu-Asp-Arg, EDR, H-Glu-Asp-Arg-OH) retrieve more records than the trade name does. It carries no US drug approval. We queried openFDA's drug-label and Drugs@FDA endpoints for the name, the sequence, and the substance field, and every query returned no match.
This note is a research-context summary. It is not a benefit claim, a protocol, or a recommendation for any human or animal use. Our Pinealon reference standards are supplied as laboratory research material, full stop.
What the published literature records
Work naming this tripeptide or its EDR sequence appears in:
- Peptide-bioregulator literature — a body of largely Russian-language publications on short regulatory peptides.
- In-vitro cell-culture studies — neuronal and other cultured cell models at the bench.
- Nucleotide-binding and sequence-interaction work — published in-vitro biochemistry on short peptide–DNA interactions.
- Analytical method work — HPLC and LC-MS separation of small, highly polar tripeptides.
- Comparator studies — side-by-side work against other short regulatory peptide sequences.
Much of this corpus is older, in translation, or in journals with limited indexing. Cite the primary record rather than a secondary summary. Nothing in that literature is an outcome claim we make about this material.
What researchers use Pinealon reference standards for
Common research contexts our customers describe:
- Analytical method development — retention behavior of a tri-acidic, highly polar peptide is its own problem on reversed-phase columns.
- Standard addition experiments — spiking a known quantity into a matrix to validate recovery.
- Purity benchmarking of in-house synthesis against a characterized external reference.
- Stability studies — behavior across storage temperatures, buffers, and pH.
- In-vitro cell-culture work per published bench protocols.
All of the above happen at the analytical bench or in cell culture. None involve a person or an animal.
Quality we ship against
Our Pinealon reference material ships with:
- Purity ≥ 99% by RP-HPLC (UV 214 nm)
- Identity confirmed by ESI-MS against the expected 418.40 g/mol molecular mass
- Salt form stated on the COA — free peptide or acetate, never left ambiguous
- Independent analytical lab COA — not self-certified
- White to off-white lyophilized powder, lot-traceable across vial, COA, and shipment record
Lots that fall short of the purity floor do not ship. The catalog reflects what passed release, not what sat in inventory.
Each line is anchored to a published procedure. Area-percent purity is only comparable when the system suitability of USP General Chapter ⟨621⟩ Chromatography holds. Identity by observed mass is framed in USP ⟨736⟩ Mass Spectrometry. The method behind either figure is validated against ICH Q2(R2), Validation of Analytical Procedures. "Independent" is checkable too — ISO/IEC 17025 accreditation is listed by NIST's NVLAP and by the ILAC Mutual Recognition Arrangement.
What is out of scope
Obscure compounds attract speculation, and we do not participate in it. Questions about human use, protocols, combinations with other compounds, or any personal-use scenario are out of scope for Elev8 Labs. We do not provide that information, and we do not supply material configured for such use. Our business ends at the analytical bench.
Analytical, identity, and lot-availability questions are welcome at support@elev8labsrx.com.
Elev8 Labs products are reference standards for laboratory research only. Not for human consumption.